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platelet-derived growth factor


Definition: a factor in platelets that is mitogenic for cells at the site of a wound, causing endothelial proliferation; cationic glycoprotein mitogen for fibroblasts, smooth muscle cells, and glial cells. Principal factor in serum required for the growth and proliferation of mesenchymal-derived cells in tissue culture.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.