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picrotoxin

Pronunciation: pik'ro-tok'sin

Definition: A bitter neutral principle derived from the fruit of Anamirta cocculus (family Menispermaceae); a CNS stimulant; a convulsant and GABA antagonist used extensively in experimental procedures studying seizure mechanisms.

Synonym(s): cocculin

[G. pikros, bitter, + toxicon, poison]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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