Pronunciation: fi-tan'ik as'id
Definition: A branched-chain fatty acid that accumulates in the serum and tissues in Refsum disease and is attributed to the hereditary absence of phytanate a-oxidase; arises from phytol and acts as an inhibitor of the a-oxidation of palmitic (hexadecanoic) acid; it also accumulates in connection with some other disorders, notably peroxisomal types.
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Examples: glitazone, GI cocktail, etc.