Skip to Content

phosphodiesterase 5 inhibitor


Definition: member of a family of phosphodiesterase inhibitors. Specifically, cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5, which breaks down cGMP and terminates its action. This is the site of action of sildenafil and similar drugs used in the treatment of erectile dysfunction.

Synonym(s): PDE5

See Also: sildenafil

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.