Definition: The compound formed from an amino acid in the Edman method of protein degradation, in which phenylisothiocyanate reacts with the amino moiety of the N-terminal amino acid to form a phenylthiocarbamoyl peptide or protein, on which weak acids act to release the phenylthiohydantoin containing the N-terminal amino acid.
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Examples: glitazone, GI cocktail, etc.
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