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phenylthiohydantoin

Pronunciation: fen'il-thi'o-hi-dan'to-in

Definition: The compound formed from an amino acid in the Edman method of protein degradation, in which phenylisothiocyanate reacts with the amino moiety of the N-terminal amino acid to form a phenylthiocarbamoyl peptide or protein, on which weak acids act to release the phenylthiohydantoin containing the N-terminal amino acid.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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