Definition: a quantitative genetic trait with a continuous distribution termed its liability; may generate two kinds of phenotype, according to whether the liability lies above or below some critical threshold at about which a radical change in behavior occurs. For instance, blood uric acid level is a liability with an approximately gaussian distribution. At a critical point of chemical saturation (the threshold), crystallization occurs and the resulting gout or nongout is a threshold trait.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.