persistent generalized lymphadenopathy
Definition: a syndrome characterized by reactive hyperplasia of lymph nodes (of at least 1 month's duration and at two different body sites, not including the inguinal area) in patients infected with the human immunodeficiency virus. The lymph node lesions progress from benign reactive hyperplasia through a stage of mixed follicular hyperplasia to follicular involution with lymphocyte depletion. Many go on to a malignant non-Hodgkin lymphoma.
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Examples: glitazone, GI cocktail, etc.