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persistent generalized lymphadenopathy

 

Definition: a syndrome characterized by reactive hyperplasia of lymph nodes (of at least 1 month's duration and at two different body sites, not including the inguinal area) in patients infected with the human immunodeficiency virus. The lymph node lesions progress from benign reactive hyperplasia through a stage of mixed follicular hyperplasia to follicular involution with lymphocyte depletion. Many go on to a malignant non-Hodgkin lymphoma.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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