Pelger-Huët nuclear anomaly
Pronunciation: pel′zhā hū-et′
Definition: congenital inhibition of lobulation in the nuclei of neutrophilic leukocytes; most cells present band or bilobulate appearance, and only an occasional cell is trilobed; it is not associated with disease, but may be confused with leukocyte “shift to left”; autosomal dominant inheritance.
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Examples: glitazone, GI cocktail, etc.