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Pronunciation: par'kin-son-izm


  1. A neurologic syndrome usually resulting from deficiency of the neurotransmitter dopamine as the consequence of degenerative, vascular, or inflammatory changes in the basal ganglia; characterized by rhythmic muscular tremors, rigidity of movement, festination, droopy posture, and masklike facies.
  2. A syndrome similar to parkinsonism. Some features seen with Parkinson disease that occur with other disorders (progressive supranuclear palsy) or as a side effect of certain medications (antipsychotic drugs).

Synonym(s): Parkinson disease, shaking palsy, trembling palsy

[J. Parkinson]

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.