- Deposition in tissues of an amyloidlike protein resembling light chains of immunoglobulins in primary amyloidosis or (particularly) in atypical amyloidosis of multiple myeloma.
- Various hereditary amyloidoses (Portuguese amyloidosis, Indiana amyloidosis) characterized by progressive hypertrophic polyneuritis with sensory changes, ataxia, paresis, and muscle atrophy due to amyloid deposits in peripheral and visceral nerves.
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