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P-glycoprotein 1


Definition: Adenosine-triphosphate-dependent cell membrane protein pump present in various tissues that removes xenobiotics. Its presence in neoplastic cells confers resistance to multiple antineoplastic agents.

Synonym(s): multidrug-resistant protein CD243

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.