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ovarian hyperstimulation syndrome


Definition: iatrogenic development of ovarian hyperstimulation that occurs when the luteotropic effects of human chorionic gonadotropin are exaggerated in a cycle in which ovarian stimulation has been done as a component of infertility treatment. The human chorionic gonadotropin is administered exogeneously to trigger ovulation after gonadotropin stimulation. It is present endogenously after implantation. Syndrome includes, to varying degrees, abdominal distention, potentially massive ovarian enlargement, and third spacing of vascular volume. It can range from moderate discomfort to life-threatening ovarian enlargement and fluid shifts.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.