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Medical Term:


Pronunciation: os'te-o-pon'tin


A secreted phosphoprotein, produced by many epithelial cell types, which is highly negatively charged and frequently associated with mineralization processes. It is found in plasma, urine, milk, and bile. Transformed cells express osteopontin in elevated levels.

Synonym(s): bone sialoprotein 1

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.