- dentistry metal (usually gold) cast restoration of the occlusal surface of a posterior tooth or the lingual surface of an anterior tooth, the entire surface of which is in dentin without side walls; retention in the anterior tooth is by pins and in the posterior by pins and/or boxes in retentive grooves in the buccal and lingual walls.
- orthopedics graft applied on the exterior of a bone.
- orthopedics graft applied to skin in native urethra in hypospadias or stricture repair.
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Examples: glitazone, GI cocktail, etc.