Definition: the formyl group or the methyl group that takes part in transformylation or transmethylation reactions; by means of these reactions, a group containing a single carbon atom is added to a compound being biosynthesized, adding a methyl group (thymidine formation), adding a hydroxymethyl group (as in serine biosynthesis), or closing a ring (purine formation).
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Examples: glitazone, GI cocktail, etc.