Definition: old term for cells recognized by monoclonal antibodies to T-lymphocyte antigens; OKT-3 cells are T lymphocytes as a class, because all share a common leukocyte differentiation antigen; OKT-4 cells are helper cells; OKT-8 cells are suppressor cells. OKT-4:OKT-8 expresses the ratio of helper to suppressor cells, sometimes used as a measure of the functional status of the immune system and thus a basis for clinical diagnosis and prognosis. Current usage favors using CD designations.
[Ortho-Kung T cell]
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.