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Okazaki fragment

Pronunciation: o-ka-za'ke

Definition: a relatively short (100–2000 bp in Escherichia coli and 100–200 bp in mammals) fragment of DNA that is later joined by DNA ligase to allow for 3' ? 5' overall chain growth during replication.

[Reiji Okazaki]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.