Skip to Content
Medical Term:


Pronunciation: nu'kle-o-fil', -fil


  1. The electron pair donor atom in a chemical reaction in which a pair of electrons is picked up by an electrophil; any reagent or substance that is attracted to a region of low electron density.
  2. Relating to a nucleophil.

Synonym(s): nucleophilic1

[nucleo- + G. philos, fond]

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.