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nuclear pore complex


Definition: a nuclear pore and its approximately 50 associated proteins that regulate the transport of materials between the nucleus and the cytoplasm. Composed of cytoplasmic fibrils, cytoplasmic ring, central framework (middle ring), nuclear ring, nuclear basket, and distal ring; a molecular mass of ~125,000 mD. It has an eightfold symmetry and is anchored to the nuclear envelope by nuclear lamina.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.