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Pronunciation: no'to-kord


  1. In primitive vertebrates, the primary axial supporting structure of the body, derived from the notochordal or head process of the early embryo; an important organizer for determining the final form of the nervous system and related structures.
  2. In embryos, the axial fibrocellular cord about which the vertebral primordia develop; vestiges of it persist in the adult as the nuclei pulposi of the intervertebral discs.

Synonym(s): chorda dorsalis

[G. notos, back, + chorde, cord, string]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.