Definition: A 13–aminoacyl peptide neurotransmitter found in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord; plays a role in pain perception but its analgesic effects are not blocked by opioid antagonists; it also affects pituitary hormone release and gastrointestinal function.
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Examples: glitazone, GI cocktail, etc.