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neuromuscular blocking agents

 

Definition: a group of drugs that prevents motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine (D-tubocurarine, mivacurium, and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to acetylcholine (succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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