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neurokinin-1 antagonist

 

Definition: agent that blocks the action of substance Pm which is a peptide found in the brain and GI tract, which initiates its actions by binding to the neurokinin-1 receptor. Antagonists of the neurokinin-1 receptor have been shown to have antiemetic activity.

See Also: substance P

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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