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nerve growth factor


Definition: a protein (MW about 27,000) that controls the development of sympathetic postganglionic neurons and possibly also sensory (dorsal root) ganglion cells in mammals; similar factors have been isolated from the venom of several species of snakes; it has been isolated from the submaxillary glands of male mice, and when it is injected into newborn animals, sympathetic ganglia become hyperplastic and hypertrophic; stimulates synthesis of nucleic acids and protein.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.