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nephrotic syndrome

 

Definition: a clinical state characterized by edema, albuminuria, decreased plasma albumin, doubly refractile bodies in the urine, and usually increased blood cholesterol; lipid droplets may be present in the cells of the renal tubules, but the basic lesion is increased permeability of the glomerular capillary basement membranes, of unknown cause or resulting from glomerulonephritis, diabetic glomerulosclerosis, systemic lupus erythematosus, amyloidosis, renal vein thrombosis, or hypersensitivity to various toxic agents.

Synonym(s): nephrosis3

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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