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negative stain

 

Definition: stain forming an opaque or colored background against which the object to be demonstrated appears as a translucent or colorless area; in electron microscopy, an electron opaque material, such as phosphotungstic acid or sodium phosphotungstate, is used to give detail to surface structure.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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