necrotizing ulcerative gingivitis
Definition: an acute or recurrent gingivitis of young and middle-aged adults characterized clinically by gingival erythema and pain, fetid odor, necrosis, and sloughing of interdental papillae and marginal gingiva that gives rise to a gray pseudomembrane; fever, regional lymphadenopathy, and other systemic manifestations also may be present. A fusiform bacillus and Treponema vincentii can be isolated from the gingival tissues in large numbers and are thought to play a significant but poorly defined role in the pathogenesis.
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Examples: glitazone, GI cocktail, etc.