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N5, N10-methylenetetrahydrofolate reductase

Pronunciation: meth'il-en-tet'ra-hi'dro-fo'lat re-duk'tas

Definition: An enzyme that converts N5,N10-methylenetetrahydrofolate to N5,N10-methenyltetrahydrofolate using NADP+; a deficiency of this enzyme results in an accumulation of l-homocysteine and severe neurological disturbances.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.