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myelofibrosis

Pronunciation: mi'e-lo-fi-bro'sis

Definition: Fibrosis of the bone marrow, especially generalized, associated with myeloid metaplasia of the spleen and other organs, leukoerythroblastic anemia, and thrombocytopenia, although the bone marrow often contains many megakaryocytes.

Synonym(s): myelosclerosis, osteomyelofibrotic syndrome

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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