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mycosis fungoides

 

Definition: a chronic progressive lymphoma arising in the skin that initially simulates eczema or other inflammatory dermatoses; the appearance of plaques is associated with acanthosis and bandlike infiltration of the upper dermis by a pleomorphic infiltrate including helper T lymphocytes with large, convoluted nuclei that also collect in clear spaces in the lower epidermis (Pautrier microabscesses); in advanced cases, ulcerated tumors and infiltration of lymph nodes may occur.

See Also: Sézary syndrome

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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