Definition: a chronic progressive lymphoma arising in the skin that initially simulates eczema or other inflammatory dermatoses; the appearance of plaques is associated with acanthosis and bandlike infiltration of the upper dermis by a pleomorphic infiltrate including helper T lymphocytes with large, convoluted nuclei that also collect in clear spaces in the lower epidermis (Pautrier microabscesses); in advanced cases, ulcerated tumors and infiltration of lymph nodes may occur.
See Also: Sézary syndrome
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