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mucocutaneous leishmaniasis


Definition: a serious disease caused by Leishmania braziliensis, L. braziliensis, and L. braziliensis panamensis endemic in southern Mexico and Central and South America, except for northern Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes; the lesions resemble the sores of cutaneous leishmaniasis caused by L. mexicana or L. tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue, buccal or nasal mucosa, and pharynx; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related etiologic agents.

Synonym(s): American leishmaniasis, leishmaniasis americana, bubas, nasopharyngeal leishmaniasis, New World leishmaniasis

See Also: espundia

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.