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Medical Term:

monophenol monooxygenase

Pronunciation: mon-o-fe'nol mon'o-oksi-jen-as'

Definition: A copper-containing oxidoreductase that catalyzes the oxidation of o-diphenols to o-quinones by O2, with the incorporation of one of the two oxygen atoms in the product; it also catalyzes the oxidation of monophenols, such as l-tyrosine, to dihydroxy-l-phenylalanine (dopa), a precursor of melanin and epinephrine (catecholamines), and can act as a catechol oxidase; a deficiency of this enzyme is observed in several forms of albinism.

Synonym(s): laccase

Synonym(s): cresolase, monophenol oxidase, tyrosinase

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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