Definition: a form of leukemia characterized by large numbers of cells that can be definitely identified as monocytes, in addition to larger, apparently related cells formed from the uncontrolled proliferation of the reticuloendothelial tissue; leukemia in which these two types of cells seem to “overrun” the usual sites of the reticuloendothelial system, and occur in conspicuous numbers in the circulating blood, is frequently referred to as the Schilling type of monocytic leukemia, or sometimes as true monocytic leukemia The disease runs an acute or subacute course in older persons, and is characterized by swelling of gums, oral ulceration, bleeding in skin or mucous membranes, secondary infection, and splenomegaly.
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