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monoclonal immunoglobulin


Definition: a homogeneous immunoglobulin resulting from the proliferation of a single clone of plasma cells; during electrophoresis of serum, it appears as a narrow band or “spike”; it is characterized by heavy chains of a single class and subclass and by light chains of a single type.

Synonym(s): M protein2, monoclonal protein, paraprotein2

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.