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mitogen

Pronunciation: mi'to-jen

Definition: A substance frequently derived from plants that stimulates mitosis and lymphocyte transformation in an antigen-nonspecific manner; includes not only lectins such as phytohemagglutinins, pokeweed mitogen, and concanavalin A, but also substances from streptococci (associated with streptolysin S) and from strains of a-toxin-producing staphylococci.

Synonym(s): transforming agent1

[mitosis + G. -gen, producing]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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