Definition: Increase in partially distopic neurons in the stratum zonale, white matter, hippocampus, and cerebellar cortex, producing an indistinct border between cortex and subcortical white matter and a columnar arrangement of cortical neurons; seen in patients with primary generalized epilepsy.
[micro- + dys- + G. genesis, production]
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Examples: glitazone, GI cocktail, etc.
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