Pronunciation: mi-ka'lis men'ten
Definition: a hypothesis that a complex is formed between an enzyme and its substrate (also known as the O'Sullivan-Tompson hypothesis), which complex then decomposes to yield free enzyme and the reaction products (also referred to as the Brown hypothesis), the latter step being the rate-determining step for the overall rate of substrate-product conversion.
[Leonor Michaelis, Maud L. Menten]
See Also: Michaelis-Menten constant, Michaelis-Menten equation
Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.