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metrotrophic test


Definition: an obsolete test for the assay of estrogenic substances; immature female rats (25–49 g) are injected subcutaneously with the hormone and killed after 6 hours, when the increase in uterine weight (due largely to imbibation of water) is taken as the criterion of estrogenic activity.

Synonym(s): Astwood test

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.