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methylation

Pronunciation: meth-i-la'shun

Definition: Addition of methyl groups; in histochemistry, used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid, the net effect being to reduce tissue basophilia and abolish metachromasia.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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