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methionine synthase


Definition: an enzyme that catalyzes the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.

Synonym(s): tetrahydrofolate methyltransferase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.