Pronunciation: me-tas'ta-sis, -sez
- The shifting of a disease or its local manifestations, from one part of the body to another, as in mumps when the symptoms referable to the parotid gland subside and the testis becomes affected.
- The spread of a disease process from one part of the body to another, as in the appearance of neoplasms in parts of the body remote from the site of the primary tumor; results from dissemination of tumor cells by the lymphatics or blood vessels or by direct extension through serous cavities or subarachnoid or other spaces.
- Transportation of bacteria from one part of the body to another, through the bloodstream (hematogenous metastasis) or through lymph channels (lymphogenous metastasis).
[G. a removing, fr. meta, in the midst of, + stasis, a placing]
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Examples: glitazone, GI cocktail, etc.