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Pronunciation: me-tas'ta-sis, -sez


  1. The shifting of a disease or its local manifestations, from one part of the body to another, as in mumps when the symptoms referable to the parotid gland subside and the testis becomes affected.
  2. The spread of a disease process from one part of the body to another, as in the appearance of neoplasms in parts of the body remote from the site of the primary tumor; results from dissemination of tumor cells by the lymphatics or blood vessels or by direct extension through serous cavities or subarachnoid or other spaces.
  3. Transportation of bacteria from one part of the body to another, through the bloodstream (hematogenous metastasis) or through lymph channels (lymphogenous metastasis).

Synonym(s): secondaries1

[G. a removing, fr. meta, in the midst of, + stasis, a placing]

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.