Definition: The stage of mitosis or meiosis in which the chromosomes become aligned on the equatorial plate of the cell separating the centromeres. In mitosis and in the second meiotic division, the centromeres of each chromosome divide and the two daughter centromeres are directed toward opposite poles of the cell; in the first division of meiosis, the centromeres do not divide but the centromeres of each pair of homologous chromosomes become directed toward opposite poles.
[meta- + G. phasis, an appearance]
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Examples: glitazone, GI cocktail, etc.