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Pronunciation: met'a-kro-ma'ze-a


  1. The condition in which a cell or tissue component takes on a color different from the dye solution with which it is stained.
  2. A change in the characteristic color of certain basic thiazine dyes, such as toluidine blue, when the dye molecules are bound in proximate array to tissue polyanionic polymers, such as glycosaminoglycans.

Synonym(s): metachromatism2

[meta- + G. chroma, color]

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