Definition: a test for sickle cell hemoglobin (Hb S); deoxygenation of cells containing Hb S is enhanced by addition of sodium metabisulfite to the blood, causing sickling visible on a slide; certain other abnormal hemoglobins (Hb CHarlem and Hb I) also sickle in this test.
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Examples: glitazone, GI cocktail, etc.