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Merkel cell tumor

Pronunciation: mer'kel

Definition: a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.

Synonym(s): primary neuroendocrine carcinoma of the skin, trabecular carcinoma

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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