Skip to Content
Medical Term:

mercapturic acid pathway


a glutathione-dependent pathway for the detoxification of a number of compounds, including arene oxides; an S-substituted glutathione is formed and ultimately converted to a mercapturic acid (an S-substituted N-acetylated l-cysteine), which is excreted; certain leukotrienes are believed to be degraded through this pathway.

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.