membrane attack complex
Definition: a complex of complement components (C5–C9) that, when activated, bind to the membrane of a target cell, penetrating it with a hydrophobic residue exteriorly and a hydrophilic residue in the interior of the cell; this allows passage of ions and water, swelling of the cell and subsequent lysis.
Synonym(s): MAC complex
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Examples: glitazone, GI cocktail, etc.