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Melnick-Needles osteodysplasty

Pronunciation: mel'nick ne'delz

Definition: a generalized skeletal dysplasia with prominent forehead and small mandible; radiographically, there are irregular ribbonlike constrictions of the ribs and tubular bones; probably X-linked [MIM*309350]. Autosomal dominant and recessive inheritance [MIM*249420] have also been suggested.

Synonym(s): Melnick-Needles syndrome, osteodysplasty

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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