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Pronunciation: mel'a-no-der'ma


  1. An abnormal darkening of the skin by deposition of excess melanin.
  2. Hyperpigmentation of the skin by melanin or deposition of dark substances such as silver, iron, and drug derivatives.

[melano- + G. derma, skin]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.