Definition: A large, nucleated, embryonic type of cell that is a precursor of erythrocytes in an abnormal erythropoietic process observed in pernicious anemia; a megaloblasts four stages of development are as follows: 1) promegaloblast, 2) basophilic megaloblast, 3) polychromatic megaloblast, 4) orthochromatic megaloblast.
[megalo- + G. blastos, + germ, sprout]
See Also: erythroblast
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